ITGB3BP

Proteína centromérica R
HUGO	6157
Símbolo	ITGB3BP
Símbolos alt.	CENP-R, CENPR, HSU37139, NRIF3, TAP20
Datos genéticos
Locus	Cr. 1 p31.3
Bases de datos
Entrez	23421
OMIM	605494
RefSeq	NP_055103
UniProt	Q13352

La proteína centromérica R (ITGB3BP) es una proteína que es codificada, en humanos, por el gen itgb3BP.^{[1] [2] [3]}

Interacciones

La proteína centromérica R ha demostrado ser capaz de interaccionar con:

• Receptor X retinoide gamma^[4]
• Ciclina A2^[5]
• NFKB1^[6]
• Receptor X retinoide alfa^[2]
• Receptor de hormona tiroidea alfa^{[4] [2]}
• CD61^{[7] [1]}

Referencias

1. ↑ ^{a b} Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (Dec 1995). «Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit». J Cell Biol 131 (3):  pp. 807–16. PMID 7593198. 
2. ↑ ^{a b c} Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (Feb 2000). «NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors». Mol Cell Biol 19 (10):  pp. 7191–202. PMID 10490654. 
3. ↑ «Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)».
4. ↑ ^{a b} Li, D; Wang F, Samuels H H (Dec. 2001). «Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation». Mol. Cell. Biol. (United States) 21 (24):  pp. 8371–84. doi:10.1128/MCB.21.24.8371-8384.2001. ISSN 0270-7306. PMID 11713274. 
5. ↑ Ohtoshi, A; Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (Jan. 2000). «beta3-endonexin as a novel inhibitor of cyclin A-associated kinase». Biochem. Biophys. Res. Commun. (UNITED STATES) 267 (3):  pp. 947–52. doi:10.1006/bbrc.1999.2007. ISSN 0006-291X. PMID 10673397. 
6. ↑ Besta, Felicitas; Massberg Steffen, Brand Korbinian, Müller Elke, Page Sharon, Grüner Sabine, Lorenz Michael, Sadoul Karin, Kolanus Waldemar, Lengyel Ernst, Gawaz Meinrad (Oct. 2002). «Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor». J. Cell. Sci. (England) 115 (Pt 20):  pp. 3879–88. ISSN 0021-9533. PMID 12244126. 
7. ↑ Fujimoto, Tetsuro-Takahiro; Katsutani Shinya, Shimomura Takeshi, Fujimura Kingo (Jan. 2002). «Novel alternatively spliced form of beta(3)-endonexin». Thromb. Res. (United States) 105 (1):  pp. 63–70. ISSN 0049-3848. PMID 11864709.